Diamond Light Source
Beamline B21 - High Automated Throughput SAXS (HATSAXS)

B21 is a dedicated solution state Small Angle X-ray Scattering (SAXS) beam line that can accommodate a wide variety of aqueous-based and some limited organic solvent-based samples. B21 utilises a bending magnet source and delivers ~3 x 10^12 photons/sec directly to the sample.

The photons are distributed over a large 0.8 x 2 mm cross-section which is particularly helpful in minimising radiation damage while enhancing the signal of the particles. Our detector is currently configured to measure a scattering vector (q) range from 0.0032 to 0.38 Å-1.

 SAXS time is offered through an application process via our users office.

Our end-station can be configured for full-automation from a 96-well plate, using the BIOSAXS robot (designed by the EMBL in Grenoble). However, we do offer Size-Exclusion Chromatography (SEC) coupled SAXS with either Superdex or Shodex SEC columns controlled by an Agilent HPLC. SAXS samples are measured through a temperature controlled capillary.

Beamline Energy Range
6 - 23 [keV]
Nathan Cowieson
  • Elastic scattering
  • Small angle scattering
  • Time-resolved scattering
  • Wide angle scattering
control/Data analysis
Control Software Type
  • GDA
Data Output Type
  • Image
Data Output Format
  • nxs