Diamond Light Source
Beamline I04-1 - Macromolecular Crystallography

I04-1 is a fixed wavelength monochromatic beamline, with its undulator in I04's straight section. The beamline was originally aimed at high-throughput data collection for well-diffracting crystals, with off-the-shelf robotics and a stable beam thanks to a simple beamline design. However, it is now fully part of the routine MX user program, for both academic and industrial users alike, since the constraints (5-fold weaker beam than I02/3/4, fixed energy) affect only a subset of MX experiments.

As of April 2015, the beamline is also offering a world-first, namely routine medium-throughtput fragment screening by crystal structure, including all steps from crystal soaking and harvesting to data analysis. D

Beamline Energy Range
13.53 [eV]
Max Flux On Sample
3 * 1011 [ph/s] @ 13.53 [eV]
Frank von Delft
  • Crystallography (biological macromolecules)
  • Medical application
control/Data analysis
Control Software Type
  • GDA
Data Output Type
  • Image
Data Output Format
  • cbf